Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance
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Diphthamide is a post-translationally modified histidine residue of eukaryotic TRANSLATION ELONGATION FACTOR 2 (eEF2) and the target of diphtheria toxin in human cells. In yeast and mammals, the 4Fe-4S cluster-containing proteins Dph1 and Dph2 catalyze the fir... ...