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Pharmacokinetic-pharmacodynamic Modeling of Amantadine Extended-release Capsule Effects on Dyskinesia in Parkinson Disease (P7-5.028)

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Objective: Evaluate pharmacokinetic/pharmacodynamic (PK/PD) relationships for the delayed- and extended-release (DR/ER) capsule formulation of amantadine in the treatment of levodopa-related dyskinesia in Parkinson disease. ... ...