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Brain communications. 2025 Mar 27;7(2):fcaf118. doi: 10.1093/braincomms/fcaf118 Q14.52025

Beyond the cerebellum: perivascular space burden in spinocerebellar ataxia type 3 extends to multiple brain regions

小脑外:第三型脊小脑萎缩病患者的脑室周围间隙损害扩展至多个脑区 翻译改进

Yonghua Huang  1  2  3, Zhiming Zhen  1  2, Lihua Deng  1  2, Peiling Ou  1  2, Linfeng Shi  1  2, Feng Shi  4, Rui Hua  4, Jiaojiao Wu  4, Wei Chen  5, Ru Wen  1  2, Jian Wang  1  2, Chen Liu  1  2

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作者单位

  • 1 7T Magnetic Resonance Imaging Translational Medical Center, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
  • 2 Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
  • 3 Department of Radiology, The 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Lanzhou 730050, China.
  • 4 Department of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
  • 5 MR Research Collaboration Teams, Siemens Healthineers Ltd., Guangzhou 510630, China.
  • DOI: 10.1093/braincomms/fcaf118 PMID: 40190350

    摘要 中英对照阅读

    <p> Spinocerebellar ataxia type 3 (SCA3) is an uncommon inherited (autosomal dominant) neurodegenerative disorder caused by abnormal accumulation of ataxin-3 protein. The perivascular space (PVS) burden reflects protein clearance and may worsen in SCA3 disease.... ...

    <p>&#33258;&#26059;&#23567;&#33041;&#20849;&#27982;&#22833;&#35843;3&#22411;&#65288;SCA3&#65289;&#26159;&#19968;&#31181;&#32597;&#35265;&#30340;&#24120;&#26579;&#33394;&#20307;&#26174;&#24615;&#36951;&#20256;&#30340;&#31070;&#32463;&#36864;&#34892;&#24615;&#30142;&#30149;&#65292;&#30001;ataxin-3&#34... ...

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    期刊名:Brain communications

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    ISSN:N/A

    e-ISSN:2632-1297

    IF/分区:4.5/Q1

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    Beyond the cerebellum: perivascular space burden in spinocerebellar ataxia type 3 extends to multiple brain regions