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HER2 mRNA Score From Quantitative ERBB2 mRNA Expression of Oncotype Dx: Can It Replace the HER2 Immunohistochemistry?

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As novel human epidermal growth factor receptor-2 (HER2) and drug conjugates have proven to be effective treatments for both HER2-positive breast cancer (BC) and HER2-low BC, the need to develop more accurate methods to quantify HER2 status has increased. We c... ...