Atp6v0d2 deficiency partially restores defects in Mcoln1-deficient mouse corpus luteum
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Objective: ATP6V0d2 is a subunit of the vacuolar-type H+-ATPase (V-ATPase) that pumps H+ ions into lysosomes. TRPML1 (MCOLN1/Mcoln1) transports cations out of lysosomes. Mcoln1 -/- mice recapitulate the lysosomal storage disorder... ...
