Variant screening of PYY3-36 leads to potent long-acting PYY analogs with superior Y2 receptor selectivity
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Peptide YY (PYY3-36) has attracted attention in diabetes and obesity research because of its involvement in food intake regulation and glucose homeostasis. Native PYY3-36 maintains high potency on the Y2 receptor with a loss of potency on the Y1, Y4, and Y5 re... ...
