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Age-associated increase in AT1R expression in human testis and its intervention effects on Leydig cell senescence in aged rodents

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The active peptide hormone Ang II (angiotensin II) mediates the vast majority of the RAS (renin-angiotensin system) action, mainly through activation of AT1R (Angiotensin II type-1 receptor). AT1R expression peaks in newborn males and decreases toward the adul... ...