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Proteins of the Triadic Excitation-Contraction Coupling Complex in Skeletal Muscle

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Excitation-contraction coupling (ECC) in skeletal muscle is mediated by mechanical coupling between the L-type voltage-dependent Ca2+ channel (CaV1.1) in the transverse tubules and the Ca2+ release channel (RYR1) in the sarcoplasmic reticulum (SR). However, EC... ...