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Label-free Aβ plaque detection in Alzheimer's disease brain tissue using infrared microscopy and neural networks

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We present a novel method for the label-free detection of amyloid-beta (Aβ) plaques, the key hallmark of Alzheimer's disease, in human brain tissue sections. Conventionally, immunohistochemistry (IHC) is employed for the characterization of Aβ plaques, hind... ...