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An endoplasmic reticulum-associated structure sequesters misassembled FG-Nups to help maintain NPC function

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Misassembly of nucleoporins (Nups), central components of the nuclear pore complex (NPC), leads to Nup mislocalization outside of the nuclear envelope. Here we elucidate the fate of mislocalized Nups. To impair Nup assembly, we depleted the structural componen... ...