Thalidomide-based regimen shows promising efficacy in large granular lymphocytic leukemia: a multicenter phase II study
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Large granular lymphocytic leukemia (LGLL) is characterized by the clonal proliferation of cytotoxic T lymphocytes or NK cells. Standard first-line immunosuppressive treatments have limitations, achieving complete remission (CR) rates of up to 50%. Immune syst... ...