Metabolic engineering of Kluyveromyces marxianus to produce myo-inositol from starch
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To efficiently produce myo-inositol from glucose, the PGI1, ZWF1, ITR2, and MIOX5 genes in Kluyveromyces marxianus were knocked out to block glucose metabolism via the Embden-Meyerhof-Parnas (EMP) and pentose phosphate pathways (PPP), prevent myo-inositol oxid... ...