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Multi-ancestry GWAS reveals loci linked to human variation in LINE-1- and Alu-insertion numbers

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LINE-1 (L1) and Alu are two families of transposable elements (TEs) occupying ~17% and ~11% of the human genome, respectively. Though only a small fraction of L1 copies is able to produce the machinery to mobilize autonomously, Alu and degenerate L1s can hijac... ...