CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer's disease
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At autopsy, around half of the Alzheimer's disease (AD) brains exhibit Lewy body pathology, and the main component of Lewy body pathology is α-synuclein aggregates. This study investigated the prevalence of cerebrospinal fluid (CSF) α-synuclein aggregation ... ...
