A simple fluorometric test method for assessing skin sensitization potential of chemicals by using N-acetyl-L-cysteine methyl ester in chemico
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The covalent binding of sensitizer to skin proteins is referred to as key event 1 of the adverse outcome pathway in skin sensitization. Recently, N-acetyl-L-cysteine methyl ester (NACME) was demonstrated to react selectively with skin sensitizers in vitro, suc... ...
