Semi-rational engineering of an α-L-fucosidase for regioselective synthesis of fucosyl- N-acetylglucosamine disaccharides
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α-L-Fucosidases are attractive biocatalysts for the production of bioactive fucosylated oligosaccharides, however, poor regioselectivity and activity for transglycosylation have significantly limited their applications. We have recently derived an α-L-Fucosi... ...