Theaflavin 3'-gallate activates G protein-coupled receptor 55 (GPR55) and enhances GLP-1 secretion via Ca2+/CaMKII/ERK signaling in enteroendocrine STC-1 cells, mitigating postprandial hyperglycemia in mice
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The antihyperglycemic effect of black tea is well-known, and theaflavins (TFs) are considered active compounds. It is, however, unclear whether glucagon-like peptide-1 (GLP-1) is involved in the antihyperglycemic effects of TFs. We demonstrate that TFs suppres... ...
