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Rat PermQ: A permeability- and perfusion-based physiologically based pharmacokinetic model for improved prediction of drug concentration-time profiles in rat

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A new rat permeability- and perfusion-limited physiologically based pharmacokinetic model, "rat PermQ," was developed with the goal of improving concentration-time (C-t) predictions of drugs. Similar to the previously published human PermQ, drugs can reversi... ...