Differential Effects of Aβ Peptides on the Plasmin-Dependent Degradation of ApoE3 and ApoE4
{{output}}
The ApoE4 allele of apolipoprotein E (ApoE4) is the strongest hereditary predisposition to Alzheimer's disease, even though ApoE4 only differs from the more common ApoE3 by a single amino acid substitution. Previous studies have shown that ApoE4 is more susce... ...