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Ezetimibe Oral Solid Lipid Nanoparticle by Effervescent Dispersion Method: in Vitro Characterization And in Vivo Pharmacokinetic Study in Rats

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Ezetimibe (EZT) is a class II drug of the Biopharmaceutics classification system (BCS), with limited aqueous solubility and high permeability. This study aims to enhance the solubility and oral bioavailability of EZT by developing EZT solid lipid nanoparticles... ...