Ribosome-associated pathological TDP-43 alters the expression of multiple mRNAs in the monkey brain
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Cytoplasmic accumulation of TDP-43 is a pathological hallmark of amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. While current studies have primarily focused on gene regulation mediated by full-length nuclear TDP-43, the potential eff... ...
