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Techniques in coloproctology. 2025 Feb 14;29(1):68. doi: 10.1007/s10151-024-03104-0 Q32.72024

Long-term outcome of laparoscopic ventral rectopexy for full-thickness rectal prolapse: the PEXITY study

腹腔镜全层直肠前固定术治疗完全性直肠脱垂的长期效果:PEXITY研究 翻译改进

M Barra  1, B Trilling  1  2, G Mastronicola  1, P-Y Sage  1, A Roudier  1, A Foote  1, F Tidadini  1, J Fournier  3, J-L Faucheron  4  5

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作者单位

  • 1 Colorectal Surgery Unit, Department of Digestive and Emergency Surgery, Michallon Hospital, Grenoble Alpes University Hospital, CS 10 217, 3843 Grenoble cedex, 38000, Grenoble, France.
  • 2 University Grenoble Alpes, CNRS UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000, Grenoble, France.
  • 3 Clinical Investigation Centre, INSERM CIC 1406, Grenoble Alpes University Hospital, Grenoble, France.
  • 4 Colorectal Surgery Unit, Department of Digestive and Emergency Surgery, Michallon Hospital, Grenoble Alpes University Hospital, CS 10 217, 3843 Grenoble cedex, 38000, Grenoble, France. JLFaucheron@chu-grenoble.fr.
  • 5 University Grenoble Alpes, CNRS UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000, Grenoble, France. JLFaucheron@chu-grenoble.fr.
  • DOI: 10.1007/s10151-024-03104-0 PMID: 39953171

    摘要 Ai翻译

    Background: Laparoscopic ventral mesh rectopexy (LVR) has gained increasing acceptance for the treatment of patients with a full-thickness rectal prolapse (RP), but literature on follow-up of at least 10 years is scarce. We studied recurrence rate, long-term functional results and quality of life in patients who had LVR for RP more than 12 years ago.

    Method: The study population consisted of patients who could be contacted among the 175 who had undergone LVR for RP and whose short- and medium-term outcomes were published in 2012. We studied the long-term recurrence rate (Kaplan-Meier), functional outcome (Wexner and ODS scores), quality of life (EuroQol) and satisfaction of the patient through clinical examination(s), specific scores and questionnaires.

    Results: Of the 175 patients, 14 patients had exclusion criteria, 57 had died, and 42 were lost to follow-up, leaving 62 patients for analysis. Seventeen patients presented with a recurrence (10.5%) at the 10-year follow-up. The only statistically significant risk factor for recurrence was recurrent RP (HR = 11.5 (2.54-52.2), P = 0.002). The median faecal incontinence score was 4 (0-10) and significantly worse in patients who had a recurrence [12 (7-13) vs 3 (0-9); P = 0.016]. The median obstructive defaecation score was 6 (3-12). The median quality of life score was 7 (6-8). Most patients who presented with a recurrence said they would undergo the operation again and recommended it, as would patients with no recurrence.

    Conclusion: LVR for RP is a safe and efficient technique with sustainable long-term results that shows long-term efficacy at > 10 years after the operation.

    Keywords: Full-thickness rectal prolapse; laparoscopic ventral rectopexy; long-term functional results; prolapse recurrence; quality of life.

    Keywords:rectal prolapse; laparoscopic ventral rectopexy; full-thickness rectal prolapse

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    期刊名:Techniques in coloproctology

    缩写:TECH COLOPROCTOL

    ISSN:1123-6337

    e-ISSN:1128-045X

    IF/分区:2.7/Q3

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    Long-term outcome of laparoscopic ventral rectopexy for full-thickness rectal prolapse: the PEXITY study