Updated patent review for Hematopoietic progenitor kinase (HPK1) inhibitors and degraders (2021-present)
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Introduction: Hematopoietic progenitor cell kinase (HPK1) is a serine/threonine kinase of MAP4K family. It negatively regulates T cell receptor and B cell signal transduction. The loss of HPK1 kinase function increases the secret... ...