ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
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Stimulator of interferon genes (STING) transmits signals downstream of the cytosolic DNA sensor cyclic guanosine monophosphate-AMP synthase (cGAS), leading to transcriptional upregulation of cytokines. However, components of the STING signaling pathway, such a... ...