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Autophagy-Activating Nanoautophagosome-Tethering Compounds for Targeted Protein Degradation Specifically in Tumor Cells

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Autophagosome-tethering compounds (ATTECs) represent an emerging targeted protein degradation (TPD) technology that directly draws intracellular proteins of interest (POIs) into autolysosomes. Although ATTECs are currently dominated by small molecules, the poo... ...