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NRF1 Transcriptionally Regulates USP1-Mediated Deubiquitination of AURKA to Facilitate Osteosarcoma Progression

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The poor prognosis of osteosarcoma (OS) lead to the low survival rate of OS patients. Numerous researches have shown that nuclear factor erythroid 2-like 1 (NRF1) can regulate the development and progression of cancer, but it has not yet been documented in OS.... ...