Synthesis and biological evaluation of oleanolic acid derivatives as potential c-kit inhibitors
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The 3-O-(4'-imidazole)-12-en-olean-28-amide derivatives 7-1 to 7-11 through modification the C-3 and C-28 of the natural product oleanolic acid were prepared, and their structures were confirmed by MS,1H NMR and 13C NMR. The antitumor activities of these comp... ...
