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Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells

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Somatic stem cell pools comprise diverse, highly specialized subsets whose individual contribution is critical for the overall regenerative function. In the bone marrow, myeloid-biased hematopoietic stem cells (myHSCs) are indispensable for replenishment of my... ...