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Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders

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IL-17A, referred to as IL-17, is the founding member of a family of pro-inflammatory cytokines, including IL-17B, IL-17C, IL-17D, IL-17E (or IL-25), and IL-17F, which act via receptors IL-17RA to IL-17RE, and elicit potent cellular responses that impact divers... ...