DDO1002, an NRF2-KEAP1 inhibitor, improves hematopoietic stem cell aging and stress response
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Oxidative stress diminishes the functionality of hematopoietic stem cells (HSCs) as age advances, with heightened reactive oxygen species (ROS) levels exacerbating DNA damage, cellular senescence, and hematopoietic impairment. DDO1002, a potent inhibitor of th... ...
