Large soluble CD18 complexes with exclusive ICAM-1-binding properties are shed during immune cell migration in inflammation
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The family of heterodimeric CD11/CD18 integrins facilitate leukocyte adhesion and migration in a wide range of normal physiologic responses, as well as in the pathology of inflammatory diseases. Soluble CD18 (sCD18) is found mainly in complexes with hydrodynam... ...
