Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47
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Botulinum neurotoxins (BoNTs) rank among the most potent toxins and many of them are produced by bacteria carrying the orfX gene cluster that also encodes four nontoxic proteins (OrfX1, OrfX2, OrfX3 and P47). The orfX gene cluster is also found in the genomes ... ...
