Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion
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Coronaviruses express their structural and accessory genes via a set of subgenomic RNAs, whose synthesis is directed by transcription regulatory sequences (TRSs) in the 5' genomic leader and upstream of each body open reading frame. In SARS-CoV-2, the TRS has... ...