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Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation

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Alzheimer's disease (AD) is an age-related neurodegenerative pathology. Brain-derived extracellular vesicles (EVs) have been demonstrated to be implicated in AD pathogenesis by facilitating the propagation of Tau, amyloid-β and inflammatory cytokines. Howeve... ...