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Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation

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During gastrulation, Wnt-β-catenin signaling dictates lineage bifurcation generating different mesoderm cell types. However, the specific role of Wnt receptors in mesoderm specification remains elusive. Using selective Frizzled (FZD) and LRP5/6 antibody-based... ...