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Characterization of a novel PET radioligand for mitochondrial complex I in nonhuman primate

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The role of mitochondrial complex I (MC-I) dysfunction is well-documented across a range of neurodegenerative disorders. Recently, a novel positron emission tomography (PET) radioligand, [18F]CNL02, has been synthesized to target MC-I. In this paper, we provid... ...