Heparin-binding of the human chitinase-like protein YKL-40 is allosterically modified by chitin oligosaccharides
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The chitinase-like protein YKL-40 (CHI3L1) has been implicated in the pathophysiology of inflammation and cancer. Recent studies highlight the growing interest in targeting and blocking the activity of YKL-40 to treat cancer. Some of those targeting-strategies... ...
