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Anticancer effect of a single-chain variable fragment against pro-matrix metalloproteinase-7 in colon cancer

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Disrupting the interaction between matrix metalloproteinase-7 (MMP-7) and syndecan-2 (SDC-2) can yield anticancer effects in colon cancer cells. Here, a single-chain variable fragment (scFv) targeting the pro-domain of MMP-7 was generated as a potential candid... ...