High-risk neuroblastoma: ATRX and TERT as prognostic markers and therapeutic targets. Review and update on the topic
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High-risk neuroblastoma continues to show a very high mortality, with a 5-year survival rate of 50%. While MYCN amplification is the main genetic alteration associated with high-risk tumours, other molecular mechanisms, such as alterations in ATRX and TERT, re... ...
