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Differential effects of endo- and exopolyphosphatase expression on the induction of the mitochondrial permeability transition pore

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Inorganic polyphosphate (polyP) is a polymer that consists of a series of orthophosphates connected by high-energy phosphoanhydride bonds, like those found in ATP. In mammalian mitochondria, polyP has been linked to the activation of the mitochondrial permeabi... ...