Spliced exon9 ADRM1 promotes liver oncogenicity via selective degradation of tumor suppressor FBXW7
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Background & aims: The ubiquitin receptor ADRM1/Rpn13 governs the specificity of eukaryotic protein degradation. By SMRT sequencing, we first discovered a novel spliced variant of ADRM1 with a skipped exon 9, termed ADRM1-ΔEx9, ... ...
