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Animal and vegetal materials of mouse oocytes segregate at first zygotic cleavage: a simple mechanism that makes the 2-cell blastomeres differ reciprocally from the start

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Recent advances in embryology have shown that the sister blastomeres of 2-cell mouse and human embryos differ reciprocally in potency. An open question is whether the blastomeres became different as opposed to originating as different. Here we wanted to test t... ...