Direct STAT3 and STAT5 Inhibition Overcomes Treatment Resistance in a Murine Derived In Vitro Model of Acute Lymphoblastic Leukaemia driven by ETV6::JAK2
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INTRODUCTION ETV6::JAK2 is a fusion known to drive Acute Lymphoblastic Leukaemia (ALL) in the presence of other genomic lesions which define the JAK/STAT class of Philadelphia-like Acute Lymphoblastic Leukaemia (Ph-like ALL). Ph-like ALL comprises approximatel... ...