Inflammatory Pathways of Sulfonamide Diuretics: Insights into SLC12A Cl- Symporters and Additional Targets
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Thiazide, thiazide-like, and loop diuretics are primarily known for inhibiting members of the SLC12A family of Cl- transporters, which include the Na+Cl- cotransporter (NCC), Na+K+2Cl- cotransporters (NKCC1 and NKCC2) and K+Cl- symporters (KCC1-4). While the m... ...
