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Enhanced pharmacokinetic approach for anastrozole in macromolecule-based silk fibroin nanoparticles incorporated in situ injectables for estrogen-positive breast cancer therapy

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Breast cancer (BC) is a substantial reason for cancer-related mortality among women across the globe. Anastrozole (ANS) is an effective orally administered hormonal therapy for estrogen+ (ER+) BC treatment. However, several side effects and pharmacokinetic lim... ...