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Multi-tiered proteome analysis displays the hyper-permeability of the rheumatoid synovial compartment for plasma proteins

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Rheumatoid arthritis (RA) is characterized by synovial hyperplasia and cartilage/bone destruction. RA affects the synovial joints, the synovial lining and the permeability of the synovium. As the latter is of central relevance for the distribution of systemica... ...