Structural characterization of codon 129 polymorphism in prion peptide segments (PrP127-132) using the Markov State Models
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The human prion protein gene (PRNP) consists of two common alleles that encode either methionine or valine residues at codon 129. Polymorphism at codon 129 of the prion protein (PRNP) gene is closely associated with genetic variations and susceptibility to spe... ...