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Mouse CD8+ T cell subsets differentially generate IL-17-expressing cells in the colon epithelium and lamina propria

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Colon-resident CD8+ T cells actively contribute to gut homeostasis and the pathogenesis of inflammatory bowel disease. However, their heterogeneity in generating IL-17-expressing CD8+ T cells, i.e. Tc17 cells, has not been thoroughly revealed. This study aims ... ...