Itaconate facilitates viral infection via alkylating GDI2 and retaining Rab GTPase on the membrane
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Metabolic reprogramming of host cells plays critical roles during viral infection. Itaconate, a metabolite produced from cis-aconitate in the tricarboxylic acid cycle (TCA) by immune responsive gene 1 (IRG1), is involved in regulating innate immune response an... ...
