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OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression

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Colorectal cancer (CRC) is an extremely harmful malignant tumor. Optic atrophy 3 (OPA3) is highly expressed in multiple tumors, but its action in CRC is still unknown. This research aims to explore the role of OPA3 and its related molecular mechanisms for CRC.... ...